Description review
Senior/Principal Scientist, Medicinal Chemistry – Peptide Drug Design
Newbridge · United States · back to the listing
HR standards
50/100
needs work
Title ↔ description
94/100
strong
Reads as
Unclear
no confident match
What the listing never says
- No section describes what the person would actually do. Scope clarity
- No pay range published. Candidates cannot tell whether applying is worth their time. Pay transparency
- No location or timezone policy stated, so a candidate cannot tell where they may work from. Scope clarity
The listing, marked up
Nothing in the wording of this listing tripped a check. The scores above still judge how complete and coherent it is.
Got it — here's a version with Our Client written out and ready to drop your client's name/branding in. Just replace [Our Client] and the bracketed details.
Senior/Principal Scientist, Medicinal Chemistry – Peptide Drug Design
Level: Senior Scientist to Associate Director | ByteDance 3-1 / 3-2 Equivalent
Location: Flexible – United States or China
About Our Client
Our Client is a clinical-stage biotech company redefining peptide therapeutics through the integration of AI-driven design, novel chemistry, and translational biology. Backed by [top-tier investors/partners], we are advancing a pipeline of First-in-Class (FIC) programs targeting [oncology, metabolic, immunology — insert TAs] with high unmet need.
We combine the scientific rigor of Big Pharma with the speed and ownership of a startup. Our team is distributed across the US and China, united by one goal: deliver breakthrough medicines to patients, faster.
The Role
We are seeking a Senior or Principal Scientist / Associate Director in Medicinal Chemistry to lead peptide drug discovery from concept to candidate. You will own the chemistry strategy for FIC programs and work shoulder-to-shoulder with computational, biology, and translational teams to compress timelines from idea to IND.
What You'll Own
• Lead design and optimization of First-in-Class peptide therapeutics against novel, high-value targets
• Drive SAR campaigns across macrocycles, stapled peptides, peptide-drug conjugates, and oral bioavailable peptides
• Partner with AI/ML, CADD, structural biology, DMPK, and pharmacology to run rapid design-make-test cycles
• Advance programs through hit-to-lead, lead optimization, and IND-enabling studies
• Represent Medicinal Chemistry on core project teams and mentor junior scientists
What You Bring
• PhD in Organic Chemistry, Medicinal Chemistry, Chemical Biology, or related field
•
8+ years industry experience at major U.S. pharmaceutical companies, with peptides/proteins taken to IND/clinic
•
Startup experience: Thrive in agile, ambiguous environments with high ownership and urgency
•
ByteDance Level 3-1 to 3-2 equivalent — Senior Scientist, Principal Scientist, or Associate Director scope
• Deep expertise in peptide design: non-canonical amino acids, cyclization, conjugation, SBDD, and peptide property optimization
•
Proven FIC track record: Invented novel mechanisms of action and advanced them into development
Why Join Our Client
•
Real shots on goal: Work on FIC programs with line of sight to patients
•
Speed + Resources: Startup velocity, backed to move programs to the clinic
•
Global + Flexible: Base in US or China, collaborate with world-class talent
•
Top-tier package: Competitive comp, significant equity, and comprehensive benefits
Originally posted on Himalayas
Senior/Principal Scientist, Medicinal Chemistry – Peptide Drug Design
Level: Senior Scientist to Associate Director | ByteDance 3-1 / 3-2 Equivalent
Location: Flexible – United States or China
About Our Client
Our Client is a clinical-stage biotech company redefining peptide therapeutics through the integration of AI-driven design, novel chemistry, and translational biology. Backed by [top-tier investors/partners], we are advancing a pipeline of First-in-Class (FIC) programs targeting [oncology, metabolic, immunology — insert TAs] with high unmet need.
We combine the scientific rigor of Big Pharma with the speed and ownership of a startup. Our team is distributed across the US and China, united by one goal: deliver breakthrough medicines to patients, faster.
The Role
We are seeking a Senior or Principal Scientist / Associate Director in Medicinal Chemistry to lead peptide drug discovery from concept to candidate. You will own the chemistry strategy for FIC programs and work shoulder-to-shoulder with computational, biology, and translational teams to compress timelines from idea to IND.
What You'll Own
• Lead design and optimization of First-in-Class peptide therapeutics against novel, high-value targets
• Drive SAR campaigns across macrocycles, stapled peptides, peptide-drug conjugates, and oral bioavailable peptides
• Partner with AI/ML, CADD, structural biology, DMPK, and pharmacology to run rapid design-make-test cycles
• Advance programs through hit-to-lead, lead optimization, and IND-enabling studies
• Represent Medicinal Chemistry on core project teams and mentor junior scientists
What You Bring
• PhD in Organic Chemistry, Medicinal Chemistry, Chemical Biology, or related field
•
8+ years industry experience at major U.S. pharmaceutical companies, with peptides/proteins taken to IND/clinic
•
Startup experience: Thrive in agile, ambiguous environments with high ownership and urgency
•
ByteDance Level 3-1 to 3-2 equivalent — Senior Scientist, Principal Scientist, or Associate Director scope
• Deep expertise in peptide design: non-canonical amino acids, cyclization, conjugation, SBDD, and peptide property optimization
•
Proven FIC track record: Invented novel mechanisms of action and advanced them into development
Why Join Our Client
•
Real shots on goal: Work on FIC programs with line of sight to patients
•
Speed + Resources: Startup velocity, backed to move programs to the clinic
•
Global + Flexible: Base in US or China, collaborate with world-class talent
•
Top-tier package: Competitive comp, significant equity, and comprehensive benefits
Originally posted on Himalayas